"Despite the proliferation of IT applications worldwide, Indigenous knowledge remains marginalized in the mainstream information technology (IT) and Information Systems (IS) discourse. This special section explores tensions and opportunities at the intersection of Indigenous knowledge and digital technologies, emphasizing the need for culturally sensitive, inclusive, and ethical approaches to technological innovation. Bridging IT and Indigenous knowledge systems can foster environmental sustainability, digital equity, and social justice while preserving rich cultural heritage. This editorial introduces the special section, which presents ground-breaking research demonstrating the role of IT in Indigenous financial inclusion, culturally sensitive partnerships, and community empowerment. It also calls for increased interdisciplinary scholarship to advance IT solutions that respect and amplify Indigenous voices. By recognizing Indigenous knowledge as a pillar of sustainable innovation, IT and IS research can contribute to a just and inclusive technological future." (Abstract)