"This document provides immunization programmes and other stakeholders with step-by-step guidance on how to effectively manage the communication response to vaccine-related events, particularly those with a potentially high impact on public trust, which are therefore considered to be a vaccine crisis [...] While there are three general phases of vaccine crisis management, this manual mainly focuses on communications actions related to the response phase. However, to provide the broader context, it also offers suggestions for assessing the communication response to vaccine-related events that may not develop into a crisis, and a short section on communication actions during the preparedness and postcrisis evaluation phases." (Introduction)