"Artificial intelligence (AI) is reshaping the way we address complex societal challenges, offering new possibilities in areas such as healthcare, climate resilience, education, and digital inclusion. The Innovate for Impact project was launched in 2024 to identify, support, and showcase practical AI solutions that bring tangible benefits to people and communities. A key part of the initiative involves the sharing of use cases, impactful AI applications and global lessons and expertise from around the world. In 2025, building on the success of its first edition, the project expanded its scope through an open call for AI use cases and AI Scholars. We received 234 use case submissions from 32 countries, out of which 160 were selected for inclusion in this interim report. These use cases span eleven key domains and reflect both the diversity of global innovation, regional solutions with lessons learnt and the practical ways in which AI is being applied to solve real-world problems." (Foreword)