"Here we discuss a unique and innovative radio-based approach to improving mental health literacy and creating a demand for mental health services—part of a larger project called 'An Integrated Approach to Addressing the Issue of Youth Depression in Malawi and Tanzania'. Grounded in theories of social and behavior change communication and edutainment, and leveraging participatory methodologies, Farm Radio International and partners Teen Mental Health and Farm Radio Trust in Malawi worked with local radio broadcasters in Malawi and Tanzania to design and deliver weekly, interactive youth radio shows about mental health. Ongoing engagement with the content, and deliberation over the messages, was facilitated through SMS feedback mechanisms, and mobile polls and quizzes delivered through the radio stations, along with school-based radio listening clubs that met weekly to listen to the programs and discuss the themes in a group. Over the course of the 45-month project, the radio shows gained immense popularity, in large part because they talked about issues that are important to youth, and incorporated the language youth use and music they prefer. The programs attracted an average of 500,000 listeners each week, and received tens of thousands of text messages and Facebook posts by young people giving feedback, telling the radio hosts about what topics they would like to hear about, and asking questions about mental health or requesting to be connected with a mental health expert. The impact of the radio was measured according to whether and to what extent the interactive media programs play a role in triggering or facilitating drivers of the process of change. These drivers include bringing about improvements in knowledge and attitudes, mobilizing a social movement, and facilitating greater social and public support to put mental health on the agenda as a topic of conversation, grounded in new understandings and new knowledge. Our findings demonstrate that an interactive radio campaign can have a marked effect on improving knowledge, decreasing stigma, and increasing demand for mental health services among youth in sub-Saharan Africa. Youth who listened to the radio programs fare better than their peers in understanding the signs and symptoms of mental health disorders and in knowing where to go if they or someone they know needs help. Further, interactive radio programs can have a direct impact on reducing stigmatizing attitudes, frequently recognized as a crucial element in promoting improved access to care." (Executive summary)